JS laboratory

The JS lab develops and implements a generalized workflow that enables high-throughput characterization of the microbiota interactions under diverse environmental conditions. We are particularly interested in the human microbiome, as it has the most direct and significant implications for human health. The intestinal microbiota plays a key role in preventing the overgrowth of pathogens, and studying their interactions under various environmental conditions could reveal species and communities with robust inhibitory potential and identify molecular mechanisms of inhibition. ​​

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The JS lab is also interested in host-microbe interactions and metabolic diseases. We study why immunocompromised people (i.e., obese/diabetic and older individuals) are more susceptible to infections with bacterial pathogens, and hope to develop novel treatment approaches for these individuals, e.g., using defined microbial therapeutics.